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The Maria Tilton (improving early breast cancer detection)
11th April 2011
Title: Improving early breast cancer detection using plasma nucleic acids
Awarded to: Dr Jacqueline Shaw
Researcher : Dr Karen Page
Department of Cancer Studies and Molecular Medicine
Commencement: June 2011
There are currently no accepted methods using body fluids, which can reliably distinguish between healthy women and women with breast cancer, or for monitoring patients after surgery, radiation therapy and chemotherapy.
We are the first group worldwide to show that specific markers, detectable in blood plasma, can distinguish between patients with breast cancer and healthy females and potentially can also predict cancer prior to imaging in women with a strong family history of breast cancer. Hence in this fellowship, we wish to develop and validate simple tests to improve early breast cancer detection, focussing on these circulating markers in blood plasma.
The clear value to cancer research is that earlier detection leads to improved patient outcome. In addition, patient benefit would also be achieved if our blood test can predict disease progression in patients, at a time when additional therapy can be given with potentially curative intent.
Scientific version available on request
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